Josep Bassaganya-Riera Selected Research

lanthionine

1/2020	The Safety, Tolerability, and Pharmacokinetics Profile of BT-11, an Oral, Gut-Restricted Lanthionine Synthetase C-Like 2 Agonist Investigational New Drug for Inflammatory Bowel Disease: A Randomized, Double-Blind, Placebo-Controlled Phase I Clinical Trial.
7/2019	Abscisic Acid Standardized Fig (Ficus carica) Extracts Ameliorate Postprandial Glycemic and Insulinemic Responses in Healthy Adults.
3/2019	Nonclinical Toxicology and Toxicokinetic Profile of an Oral Lanthionine Synthetase C-Like 2 (LANCL2) Agonist, BT-11.
1/2017	Lanthionine Synthetase C-Like 2 Modulates Immune Responses to Influenza Virus Infection.
1/2017	Modeling new immunoregulatory therapeutics as antimicrobial alternatives for treating Clostridium difficile infection.
11/2016	An N,N-Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A Novel Lanthionine Synthetase C-Like 2-Based Therapeutic for Inflammatory Bowel Disease.
1/2016	Modeling the Role of Lanthionine Synthetase C-Like 2 (LANCL2) in the Modulation of Immune Responses to Helicobacter pylori Infection.
1/2016	Exploratory Studies With BT-11: A Proposed Orally Active Therapeutic for Crohn's Disease.
10/2012	Expression of PPAR γ in intestinal epithelial cells is dispensable for the prevention of colitis by dietary abscisic acid.
3/2011	Molecular modeling of lanthionine synthetase component C-like protein 2: a potential target for the discovery of novel type 2 diabetes prophylactics and therapeutics.

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Josep Bassaganya-Riera Research Topics

Disease

32	Inflammation (Inflammations) 01/2022 - 07/2002
18	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 09/2004
18	Colitis 01/2018 - 07/2002
14	Obesity 01/2020 - 12/2006
10	Infections 12/2017 - 01/2010
7	Insulin Resistance 01/2020 - 02/2007
6	Crohn Disease (Crohn's Disease) 01/2022 - 10/2012
4	Ulcerative Colitis 01/2022 - 03/2019
4	Virus Diseases (Viral Diseases) 10/2021 - 10/2003
4	Clostridium Infections 01/2021 - 08/2014
4	Type 2 Diabetes Mellitus (MODY) 07/2019 - 01/2010
4	Neoplasms (Cancer) 01/2017 - 07/2002
3	Body Weight (Weight, Body) 01/2020 - 06/2010
3	Communicable Diseases (Infectious Diseases) 01/2017 - 01/2012
3	Autoimmune Diseases (Autoimmune Disease) 11/2016 - 07/2002
3	Malnutrition (Nutritional Deficiencies) 01/2014 - 01/2013
3	Weight Loss (Weight Reduction) 01/2014 - 04/2010
3	Weight Gain 01/2012 - 10/2010
2	Immune System Diseases (Immune Disorders) 01/2017 - 07/2014
2	Diarrhea 01/2015 - 01/2014
2	Colonic Neoplasms (Colon Cancer) 12/2011 - 01/2009
2	Atherosclerosis 12/2010 - 07/2002
2	Colorectal Neoplasms (Colorectal Cancer) 09/2010 - 03/2010
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2008 - 12/2006
2	Hypertrophy 01/2008 - 02/2007
1	Hemorrhage 01/2022
1	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2021
1	Hyperplasia 10/2021
1	Invasive Pulmonary Aspergillosis 01/2020
1	Prediabetic State (Prediabetes) 07/2019
1	Hypersensitivity (Allergy) 01/2017
1	Papillomavirus Infections 01/2017
1	Reinfection 01/2017
1	Histiocytic Sarcoma 05/2016
1	Carcinogenesis 05/2016
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2015
1	Breast Neoplasms (Breast Cancer) 08/2014

Drug/Important Bio-Agent (IBA)

17	PPAR gammaIBA 01/2012 - 07/2002
16	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2013 - 06/2006
13	Abscisic AcidIBA 01/2020 - 02/2007
10	lanthionineIBA 01/2020 - 03/2011
10	Ligases (Synthetase)IBA 01/2020 - 03/2011
10	Conjugated Linoleic AcidsIBA 08/2016 - 07/2002
9	Insulin (Novolin)FDA Link 01/2020 - 04/2008
9	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 02/2007
7	Dextrans (Dextran)FDA Link 01/2018 - 06/2006
6	CytokinesIBA 12/2019 - 07/2002
6	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2017 - 06/2006
5	punicic acidIBA 06/2013 - 04/2009
4	Pharmaceutical PreparationsIBA 11/2016 - 06/2014
4	Proteins (Proteins, Gene)FDA Link 08/2014 - 03/2011
4	Plant Growth Regulators (Plant Hormones)IBA 06/2013 - 04/2008
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 01/2015
3	LigandsIBA 06/2014 - 12/2006
3	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 06/2010 - 01/2010
2	NX-13IBA 01/2022 - 12/2019
2	Antigen-Antibody Complex (Immune Complex)IBA 10/2021 - 01/2015
2	Blood Glucose (Blood Sugar)IBA 01/2020 - 01/2012
2	Interleukin-10 (Interleukin 10)IBA 01/2017 - 07/2002
2	Antiviral Agents (Antivirals)IBA 01/2017 - 10/2003
2	Pattern Recognition ReceptorsIBA 01/2015 - 12/2014
2	nitazoxanide (NTZ)FDA Link 08/2014 - 06/2013
2	Interleukin-17 (Interleukin 17)IBA 07/2014 - 01/2013
2	Virulence Factors (Pathogenicity Factors)IBA 07/2014 - 06/2013
2	Interferon-gamma (Interferon, gamma)IBA 07/2014 - 07/2002
2	Biological ProductsIBA 02/2014 - 01/2014
2	eleostearic acidIBA 06/2013 - 01/2011
2	Dietary Fiber FDA Link 06/2013 - 07/2011
2	AntigensIBA 01/2013 - 01/2007
2	AzoxymethaneIBA 12/2011 - 03/2010
2	Rosiglitazone (Avandia)FDA Link 01/2011 - 10/2010
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 09/2010 - 06/2006
2	DystrophinIBA 06/2010 - 06/2009
2	Messenger RNA (mRNA)IBA 02/2007 - 10/2003
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 02/2007 - 06/2006
2	Vitamin D FDA LinkGeneric 01/2007 - 07/2002
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2022
1	VaccinesIBA 10/2021
1	Imiquimod (Aldara)FDA LinkGeneric 10/2021
1	micaIBA 01/2021
1	Investigational DrugsIBA 01/2020
1	Interleukin-8 (Interleukin 8)IBA 12/2019
1	Interleukin-6 (Interleukin 6)IBA 12/2019
1	IonomycinIBA 12/2019
1	Dextran SulfateIBA 12/2019
1	Glutamine (L-Glutamine)FDA Link 01/2018
1	SodiumIBA 01/2018
1	DiazooxonorleucineIBA 01/2018
1	RNA (Ribonucleic Acid)IBA 12/2017
1	NucleotidesIBA 01/2017
1	AntibodiesIBA 01/2017
1	N,N- bis(benzimidazolylpicolinoyl)piperazineIBA 11/2016
1	Urethane (Ethyl Carbamate)IBA 05/2016
1	AS 8IBA 01/2016
1	DNA (Deoxyribonucleic Acid)IBA 01/2015
1	amixicileIBA 08/2014
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 08/2014

Therapy/Procedure

11	Therapeutics 01/2020 - 08/2010
1	Glycemic Control 01/2020
1	Fecal Microbiota Transplantation 01/2017